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The Study

The effects of Nutrova Collagen+Antioxidants on skin health were evaluated on a group of 34 women, aged 35-45 years, over a period of 60 days.

Prior to using Nutrova Collagen+Antioxidants, participants were given a placebo for 30 days to establish a baseline for comparison.

Measurements were taken using specialized instrumentation, 3D imaging and clinical evaluation by a specialist at four time points, namely:

  • The start of the study (Day -30)
  • After 30 days of placebo consumption (Day 0)
  • After 30 days of Nutrova Collagen+Antioxidants (Day 30)
  • After 60 days of Nutrova Collagen+Antioxidants (Day 60)


This study is registered at the Clinical Trial Registry of India (CTRI) with registration number CTRI/2018/07/14808.

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Day 30 Results

After 30 days, there was a significant improvement in some parameters, while others showed marginal changes.

  • Wrinkle width in the crow’s feet area reduced, which was measured using 3D image analysis.
  • There was a reduction in skin roughness, also measured using 3D image analysis.
  • Levels of melanin in pigmented spots reduced and the spots got lighter. The level of pigmentation of the spots was measured using 3D image analysis.
  • Skin firmness increased. This was measured using a Cutometer®, a specialized device that measures the skin’s ability to withstand a stretching force.
  • Skin elasticity, also measured with a Cutometer®, showed improvements at Day 30.

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Day 60 Results

After 60 days, additional parameters began to show significant changes.

  • Water loss through the skin, known as transepidermal water loss (TEWL) reduced. This was measured using a Vapometer which measures the water evaporating from the skins surface.
  • Skin hydration, measured using a Moisturemeter SC, increased.
  • Under-eye dark circles, evaluated clinically by a specialist, reduced.
  • Skin pore size, measured using 3D image analysis, reduced.
  • Skin firmness, wrinkle width, skin roughness and pigmentation of spots showed significant improvements at Day 60 as well.

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There were no significant changes through the 30 day of using the placebo (Day -30 to Day 0). However, there were significant improvements at Day 30 and Day 60 of using Nutrova Collagen+Antioxidants as mentioned above, measured using specialized instruments as well as on clinical evaluation by a specialist.

These results show that Nutrova Collagen+Antioxidants significantly improved parameters of skin health when taken daily for 30 and 60 days.

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Product Acceptability

Additionally, participants also completed self- assessment questionnaires through the study.

The questionnaires covered their own perception of their skin health as well as their feedback on the acceptability of the product (in terms of taste and digestibility) taken over time.

Feedback was unanimously positive (left), and the product was well-tolerated by all participants.

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Parameters such as skin hydration, skin firmness, pore size and skin roughness are not just measures of skin health but also directly impact how our skin looks.

The improvements through the study were statistically significant at three levels of analysis, namely:

(a) Objective measurement by specialized instruments

(b) Clinical evaluation by a specialist

(c) Self-assessment by participants


The study shows that a daily dose of Nutrova Collagen+Antioxidants is a safe, effective and convenient way to take charge of your skin health!

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